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According to placebo-controlled clinical data published in the journal Kidney Medicine, topical application of a cream containing CBD and THC reduces itch severity in patients with chronic kidney disease (CKD)- associated pruritus.

Investigators associated with Thammasat University in Thailand assessed the use of a cannabis-infused cream versus placebo in pruritus patients. Subjects were administered either the cream or the placebo for four weeks. Patients were assessed at baseline and at two weeks and four weeks.

Compared to the placebo group, kidney disease patients using the cannabis-infused cream experienced less itching and improved quality of life.

The study’s authors concluded: “This study demonstrated that a cannabis-containing cream might be an effective treatment for CKD-associated pruritus in hemodialysis patients with limited adverse side effects. Further studies with larger sample sizes and longer durations of follow-up are suggested to ensure the reliability of the results, especially regarding itch-related quality of life.”

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