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Research on the use of marijuana components to aid weight loss found that the use of a combined product containing the cannabinoids THCV and CBD “was associated with statistically significant weight loss,” as well as a slimmer waistline, lower blood pressure, and decreased cholesterol.

“Use of the THCV/CBD strip was associated with statistically significant weight loss, decreases in abdominal girth, systolic blood pressure, and total and LDL cholesterol,” says the report, authored by Dr. Gregory Smith, the founder and CEO of plant-based medicine company NeX Therapeutics, based in Florida. 

Participants were given either a placebo or one of two different mucoadhesive oral strips. A lower-dose version contained 8 milligrams of THCV and 10 mg CBD, while a higher-dose version had 16 mg THCV and 20 mg CBD. Subjects received a reminder to take a dose each day on an empty stomach and report any side effects, and they agreed to refrain from using cannabis or other cannabinoid-based products. Participants were not asked to make any changes to their diet or exercise routines.

Results showed that roughly 68% of participants who received THC or CBD lost weight, averaging about 7 pounds lost in a 90 day period. Also, about 82% of the participants saw reductions in abdominal girth.

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